Spontaneous Spinal Epidural Hematoma During Simultaneous Tocilizumab and Warfarin Use in a Patient With Rheumatoid Arthritis: Is There a Drug Interaction Between Tocilizumab and Oral Anticoagulants?

Interleukin 6 (IL-6) plays a main role in the immunopathogenesis of rheumatoid arthritis (RA). Tocilizumab (TCZ) is a humanized immunoglobulin G1 monoclonal antibody against the human IL-6. Warfarin sodium is an oral anticoagulant that is primarily metabolized by cytochrome P450 2C9 (CYP2C9). Impair...

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Detalles Bibliográficos
Autores principales: GÜNEŞ, Seçilay, GÖK, Haydar, ATAMAN, Şebnem, KUTLAY, Şehim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Turkish League Against Rheumatism 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7945701/
https://www.ncbi.nlm.nih.gov/pubmed/33758819
http://dx.doi.org/10.46497/ArchRheumatol.2020.7579

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