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Combined Administration of Metformin and Atorvastatin Attenuates Diabetic Cardiomyopathy by Inhibiting Inflammation, Apoptosis, and Oxidative Stress in Type 2 Diabetic Mice

Diabetic cardiomyopathy (DCM), a common complication of diabetes mellitus, may eventually leads to irreversible heart failure. Metformin is the cornerstone of diabetes therapy, especially for type 2 diabetes. Statins are widely used to reduce the risk of cardiovascular diseases. In this study, we ai...

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Detalles Bibliográficos
Autores principales: Jia, Weikun, Bai, Tao, Zeng, Jiang, Niu, Zijing, Fan, Daogui, Xu, Xin, Luo, Meiling, Wang, Peijian, Zou, Qingliang, Dai, Xiaozhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7945946/
https://www.ncbi.nlm.nih.gov/pubmed/33718370
http://dx.doi.org/10.3389/fcell.2021.634900

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