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Sustained neural rhythms reveal endogenous oscillations supporting speech perception

Rhythmic sensory or electrical stimulation will produce rhythmic brain responses. These rhythmic responses are often interpreted as endogenous neural oscillations aligned (or “entrained”) to the stimulus rhythm. However, stimulus-aligned brain responses can also be explained as a sequence of evoked...

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Detalles Bibliográficos
Autores principales: van Bree, Sander, Sohoglu, Ediz, Davis, Matthew H., Zoefel, Benedikt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946281/
https://www.ncbi.nlm.nih.gov/pubmed/33635855
http://dx.doi.org/10.1371/journal.pbio.3001142
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author van Bree, Sander
Sohoglu, Ediz
Davis, Matthew H.
Zoefel, Benedikt
author_facet van Bree, Sander
Sohoglu, Ediz
Davis, Matthew H.
Zoefel, Benedikt
author_sort van Bree, Sander
collection PubMed
description Rhythmic sensory or electrical stimulation will produce rhythmic brain responses. These rhythmic responses are often interpreted as endogenous neural oscillations aligned (or “entrained”) to the stimulus rhythm. However, stimulus-aligned brain responses can also be explained as a sequence of evoked responses, which only appear regular due to the rhythmicity of the stimulus, without necessarily involving underlying neural oscillations. To distinguish evoked responses from true oscillatory activity, we tested whether rhythmic stimulation produces oscillatory responses which continue after the end of the stimulus. Such sustained effects provide evidence for true involvement of neural oscillations. In Experiment 1, we found that rhythmic intelligible, but not unintelligible speech produces oscillatory responses in magnetoencephalography (MEG) which outlast the stimulus at parietal sensors. In Experiment 2, we found that transcranial alternating current stimulation (tACS) leads to rhythmic fluctuations in speech perception outcomes after the end of electrical stimulation. We further report that the phase relation between electroencephalography (EEG) responses and rhythmic intelligible speech can predict the tACS phase that leads to most accurate speech perception. Together, we provide fundamental results for several lines of research—including neural entrainment and tACS—and reveal endogenous neural oscillations as a key underlying principle for speech perception.
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spelling pubmed-79462812021-03-19 Sustained neural rhythms reveal endogenous oscillations supporting speech perception van Bree, Sander Sohoglu, Ediz Davis, Matthew H. Zoefel, Benedikt PLoS Biol Research Article Rhythmic sensory or electrical stimulation will produce rhythmic brain responses. These rhythmic responses are often interpreted as endogenous neural oscillations aligned (or “entrained”) to the stimulus rhythm. However, stimulus-aligned brain responses can also be explained as a sequence of evoked responses, which only appear regular due to the rhythmicity of the stimulus, without necessarily involving underlying neural oscillations. To distinguish evoked responses from true oscillatory activity, we tested whether rhythmic stimulation produces oscillatory responses which continue after the end of the stimulus. Such sustained effects provide evidence for true involvement of neural oscillations. In Experiment 1, we found that rhythmic intelligible, but not unintelligible speech produces oscillatory responses in magnetoencephalography (MEG) which outlast the stimulus at parietal sensors. In Experiment 2, we found that transcranial alternating current stimulation (tACS) leads to rhythmic fluctuations in speech perception outcomes after the end of electrical stimulation. We further report that the phase relation between electroencephalography (EEG) responses and rhythmic intelligible speech can predict the tACS phase that leads to most accurate speech perception. Together, we provide fundamental results for several lines of research—including neural entrainment and tACS—and reveal endogenous neural oscillations as a key underlying principle for speech perception. Public Library of Science 2021-02-26 /pmc/articles/PMC7946281/ /pubmed/33635855 http://dx.doi.org/10.1371/journal.pbio.3001142 Text en © 2021 van Bree et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
van Bree, Sander
Sohoglu, Ediz
Davis, Matthew H.
Zoefel, Benedikt
Sustained neural rhythms reveal endogenous oscillations supporting speech perception
title Sustained neural rhythms reveal endogenous oscillations supporting speech perception
title_full Sustained neural rhythms reveal endogenous oscillations supporting speech perception
title_fullStr Sustained neural rhythms reveal endogenous oscillations supporting speech perception
title_full_unstemmed Sustained neural rhythms reveal endogenous oscillations supporting speech perception
title_short Sustained neural rhythms reveal endogenous oscillations supporting speech perception
title_sort sustained neural rhythms reveal endogenous oscillations supporting speech perception
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946281/
https://www.ncbi.nlm.nih.gov/pubmed/33635855
http://dx.doi.org/10.1371/journal.pbio.3001142
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