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Engineered human meniscus’ matrix-forming phenotype is unaffected by low strain dynamic compression under hypoxic conditions

Low oxygen and mechanical loading may play roles in regulating the fibrocartilaginous phenotype of the human inner meniscus, but their combination in engineered tissues remains unstudied. Here, we investigated how continuous low oxygen (“hypoxia”) combined with dynamic compression would affect the f...

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Detalles Bibliográficos
Autores principales: Szojka, Alexander R. A., Moore, Colleen N., Liang, Yan, Andrews, Stephen H. J., Kunze, Melanie, Mulet-Sierra, Aillette, Jomha, Nadr M., Adesida, Adetola B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946300/
https://www.ncbi.nlm.nih.gov/pubmed/33690647
http://dx.doi.org/10.1371/journal.pone.0248292