Epigenomic characterization of latent HIV infection identifies latency regulating transcription factors

Transcriptional silencing of HIV in CD4 T cells generates a reservoir of latently infected cells that can reseed infection after interruption of therapy. As such, these cells represent the principal barrier to curing HIV infection, but little is known about their characteristics. To further our unde...

Descripción completa

Detalles Bibliográficos
Autores principales: Jefferys, Stuart R., Burgos, Samuel D., Peterson, Jackson J., Selitsky, Sara R., Turner, Anne-Marie W., James, Lindsey I., Tsai, Yi-Hsuan, Coffey, Alisha R., Margolis, David M., Parker, Joel, Browne, Edward P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946360/
https://www.ncbi.nlm.nih.gov/pubmed/33635929
http://dx.doi.org/10.1371/journal.ppat.1009346

Ejemplares similares

Ejemplares similares