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Recent advances in understanding assembly of the primary cilium membrane

Ciliogenesis describes the assembly of cilia in interphase cells. Several hundred proteins have been linked to ciliogenesis, which proceeds through a highly coordinated multistage process at the distal end of centrioles requiring membranes. In this short review, we focus on recently reported insight...

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Detalles Bibliográficos
Autores principales: Shakya, Saurabh, Westlake, Christopher J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Faculty Opinions Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946393/
https://www.ncbi.nlm.nih.gov/pubmed/33718933
http://dx.doi.org/10.12703/r/10-16
Descripción
Sumario:Ciliogenesis describes the assembly of cilia in interphase cells. Several hundred proteins have been linked to ciliogenesis, which proceeds through a highly coordinated multistage process at the distal end of centrioles requiring membranes. In this short review, we focus on recently reported insights into the biogenesis of the primary cilium membrane and its association with other ciliogenic processes in the intracellular ciliogenesis pathway.