Recent advances in understanding assembly of the primary cilium membrane

Ciliogenesis describes the assembly of cilia in interphase cells. Several hundred proteins have been linked to ciliogenesis, which proceeds through a highly coordinated multistage process at the distal end of centrioles requiring membranes. In this short review, we focus on recently reported insight...

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Detalles Bibliográficos
Autores principales: Shakya, Saurabh, Westlake, Christopher J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Faculty Opinions Ltd 2021
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946393/
https://www.ncbi.nlm.nih.gov/pubmed/33718933
http://dx.doi.org/10.12703/r/10-16
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author Shakya, Saurabh
Westlake, Christopher J
author_facet Shakya, Saurabh
Westlake, Christopher J
author_sort Shakya, Saurabh
collection PubMed
description Ciliogenesis describes the assembly of cilia in interphase cells. Several hundred proteins have been linked to ciliogenesis, which proceeds through a highly coordinated multistage process at the distal end of centrioles requiring membranes. In this short review, we focus on recently reported insights into the biogenesis of the primary cilium membrane and its association with other ciliogenic processes in the intracellular ciliogenesis pathway.
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spelling pubmed-79463932021-03-12 Recent advances in understanding assembly of the primary cilium membrane Shakya, Saurabh Westlake, Christopher J Fac Rev Review Article Ciliogenesis describes the assembly of cilia in interphase cells. Several hundred proteins have been linked to ciliogenesis, which proceeds through a highly coordinated multistage process at the distal end of centrioles requiring membranes. In this short review, we focus on recently reported insights into the biogenesis of the primary cilium membrane and its association with other ciliogenic processes in the intracellular ciliogenesis pathway. Faculty Opinions Ltd 2021-02-22 /pmc/articles/PMC7946393/ /pubmed/33718933 http://dx.doi.org/10.12703/r/10-16 Text en Copyright: © 2021 Westlake CJ et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Shakya, Saurabh
Westlake, Christopher J
Recent advances in understanding assembly of the primary cilium membrane
title Recent advances in understanding assembly of the primary cilium membrane
title_full Recent advances in understanding assembly of the primary cilium membrane
title_fullStr Recent advances in understanding assembly of the primary cilium membrane
title_full_unstemmed Recent advances in understanding assembly of the primary cilium membrane
title_short Recent advances in understanding assembly of the primary cilium membrane
title_sort recent advances in understanding assembly of the primary cilium membrane
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946393/
https://www.ncbi.nlm.nih.gov/pubmed/33718933
http://dx.doi.org/10.12703/r/10-16
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