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Insight into the role of phosphatidylserine in complement-mediated synapse loss in Alzheimer’s disease
The innate immune system plays an integral role in the brain. Synaptic pruning, a fundamental process in developmental circuit refinement, is partially mediated by neuroimmune signalling at the synapse. In particular, microglia, the major tissue-resident macrophages of the brain, and the classical c...
Autores principales: | Sokolova, Dimitra, Childs, Thomas, Hong, Soyon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Faculty Opinions Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946395/ https://www.ncbi.nlm.nih.gov/pubmed/33718936 http://dx.doi.org/10.12703/r/10-19 |
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