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Bidirectional regulation of glial potassium buffering – glioprotection versus neuroprotection

Glia modulate neuronal excitability and seizure sensitivity by maintaining potassium and water homeostasis. A salt inducible kinase 3 (SIK3)-regulated gene expression program controls the glial capacity to buffer K(+) and water in Drosophila, however upstream regulatory mechanisms are unknown. Here,...

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Detalles Bibliográficos
Autores principales: Li, Hailun, Lones, Lorenzo, DiAntonio, Aaron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946421/
https://www.ncbi.nlm.nih.gov/pubmed/33646119
http://dx.doi.org/10.7554/eLife.62606