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Theory for the optimal detection of time-varying signals in cellular sensing systems

Living cells often need to measure chemical concentrations that vary in time, yet how accurately they can do so is poorly understood. Here, we present a theory that fully specifies, without any adjustable parameters, the optimal design of a canonical sensing system in terms of two elementary design...

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Detalles Bibliográficos
Autores principales: Malaguti, Giulia, ten Wolde, Pieter Rein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946427/
https://www.ncbi.nlm.nih.gov/pubmed/33594978
http://dx.doi.org/10.7554/eLife.62574