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FOXA3, a Negative Regulator of Nur77 Expression and Activity in Testicular Steroidogenesis

Biosynthesis of testosterone occurs mainly in the testicular Leydig cells. Nur77, an orphan nuclear receptor that is expressed in response to the luteinizing hormone/cyclic adenosine monophosphate (LH/cAMP) signaling pathway, is one of the key factors that regulate steroidogenesis in Leydig cells. T...

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Detalles Bibliográficos
Autores principales: Kim, Hansle, Kumar, Sudeep, Lee, Keesook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946474/
https://www.ncbi.nlm.nih.gov/pubmed/33763129
http://dx.doi.org/10.1155/2021/6619447