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Mechanisms of Trx2/ASK1-Mediated Mitochondrial Injury in Pemphigus Vulgaris
OBJECTIVE: Apoptotic events mediated by mitochondrial injury play an important role on the onset of Pemphigus vulgaris (PV). The thioredoxin-2 (Trx2)/apoptosis signal-regulating kinase 1 (ASK1) signaling pathway is considered a key cascade involved on the regulation of mitochondrial injury. Hence, w...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Hindawi
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946479/ https://www.ncbi.nlm.nih.gov/pubmed/33763469 http://dx.doi.org/10.1155/2021/2471518 |