Pleomorphic Carcinoma with Exophthalmos and a Subsequent Diagnosis of Paraneoplastic Syndrome

The patient was a 75-year-old man who developed polyopia and exophthalmos. Chest computed tomography (CT) revealed a mass in the left upper lobe. A CT-guided biopsy suggested lung adenocarcinoma. He was treated by neoadjuvant chemotherapy followed by left upper lobectomy. He was diagnosed with stage...

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Detalles Bibliográficos
Autores principales: Kuzunishi, Yutaro, Tsuzuku, Akifumi, Asano, Fumihiro, Sasaki, Yui, Matsuno, Rina, Taguchi, Mayuka, Muto, Yuya, Tsuchida, Masaaki, Baba, Yasutomo, Kato, Tomoya, Murakami, Anri, Masuda, Atsunori, Daido, Hisashi, Matsumoto, Shinsuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946491/
https://www.ncbi.nlm.nih.gov/pubmed/32999228
http://dx.doi.org/10.2169/internalmedicine.5286-20
Descripción
Sumario:The patient was a 75-year-old man who developed polyopia and exophthalmos. Chest computed tomography (CT) revealed a mass in the left upper lobe. A CT-guided biopsy suggested lung adenocarcinoma. He was treated by neoadjuvant chemotherapy followed by left upper lobectomy. He was diagnosed with stage IIB pleomorphic carcinoma postoperatively. Preoperative head magnetic resonance imaging revealed exophthalmos and bilateral swelling of the extraocular muscles. The thyroid function of the patient was within the normal range, and he tested negative for autoantibodies. As his symptoms and swelling of the extraocular muscles improved postoperatively, he was diagnosed with paraneoplastic syndrome.

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