Localized Gastric Amyloidosis that Displayed Morphological Changes over 10 Years of Observation

We herein report an extremely rare case of localized gastric amyloidosis (LGA) with morphological changes during the follow-up. A 71-year-old woman who had a depressed lesion with central elevation in the gastric lower body was diagnosed with LGA. Esophagogastroduodenoscopy at 10 years after the ini...

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Detalles Bibliográficos
Autores principales: Takahashi, Yasushi, Hatta, Waku, Koike, Tomoyuki, Ogata, Yohei, Fujiya, Taku, Saito, Masahiro, Jin, Xiaoyi, Nakagawa, Kenichiro, Kanno, Takeshi, Asanuma, Kiyotaka, Uno, Kaname, Asano, Naoki, Imatani, Akira, Fujishima, Fumiyoshi, Katoh, Nagaaki, Yoshinaga, Tsuneaki, Masamune, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946503/
https://www.ncbi.nlm.nih.gov/pubmed/32999220
http://dx.doi.org/10.2169/internalmedicine.5031-20
Descripción
Sumario:We herein report an extremely rare case of localized gastric amyloidosis (LGA) with morphological changes during the follow-up. A 71-year-old woman who had a depressed lesion with central elevation in the gastric lower body was diagnosed with LGA. Esophagogastroduodenoscopy at 10 years after the initial examination showed that the lesion had grown and changed morphologically, exhibiting a submucosal tumor-like appearance. Since the lesion was confined to the submucosa, the patient underwent endoscopic submucosal dissection. The final pathological diagnosis was amyloid light-chain (AL)-type LGA. This case may provide useful information regarding the natural history of AL-type LGA.

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