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GSK3 Kinase Inhibitor, CHIR, Suppress Transcription of Tissue Specific POU2F1 Isoform in Burkitt Namalwa Lymphoma Cells

POU2F1 (Oct-1) is a transcription factor, the overexpression of which is found in many human malignant tumors; a significant increase in its level in cells determines the malignant potential of the tumor. POU2F1 is represented in cells by several isoforms that are transcribed from alternative promot...

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Detalles Bibliográficos
Autores principales: Pankratova, E. V., Portseva, T. N., Makarova, A. A., Ilyin, Yu. V., Stepchenko, A. G., Georgieva, S. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pleiades Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946658/
https://www.ncbi.nlm.nih.gov/pubmed/33689071
http://dx.doi.org/10.1134/S1607672921010087