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Unlocking the Recovery Potential: JMJD3 Inhibition-Mediated SAPK/JNK Signaling Inactivation Supports Endogenous Oligodendrocyte-Lineage Commitment Post Mammalian Spinal Cord Injury

Spinal cord injury (SCI) induced catastrophic neurological disability is often incurable at present. The injury triggered immediately oligodendrocytes loss and overwhelming demyelination are regarded as an insurmountable barrier to SCI recovery. To date, effective strategy to promote the endogenous...

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Detalles Bibliográficos
Autores principales: Bo-Yin, Zhang, Qingsan, Zhu, Yihang, Ma, Fan, Yang, Yuhang, Zhu, Pengyu, Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946673/
https://www.ncbi.nlm.nih.gov/pubmed/33428096
http://dx.doi.org/10.1007/s11064-020-03210-z

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