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Unlocking the Recovery Potential: JMJD3 Inhibition-Mediated SAPK/JNK Signaling Inactivation Supports Endogenous Oligodendrocyte-Lineage Commitment Post Mammalian Spinal Cord Injury
Spinal cord injury (SCI) induced catastrophic neurological disability is often incurable at present. The injury triggered immediately oligodendrocytes loss and overwhelming demyelination are regarded as an insurmountable barrier to SCI recovery. To date, effective strategy to promote the endogenous...
Autores principales: | Bo-Yin, Zhang, Qingsan, Zhu, Yihang, Ma, Fan, Yang, Yuhang, Zhu, Pengyu, Chang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946673/ https://www.ncbi.nlm.nih.gov/pubmed/33428096 http://dx.doi.org/10.1007/s11064-020-03210-z |
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