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A novel temporal‐predominant neuro‐astroglial tauopathy associated with TMEM106B gene polymorphism in FTLD/ALS‐TDP
Polymorphisms in TMEM106B, a gene on chromosome 7p21.3 involved in lysosomal trafficking, correlates to worse neuropathological, and clinical outcomes in frontotemporal lobar degeneration (FTLD) and amyotrophic lateral sclerosis (ALS) with TDP‐43 inclusions. In a small cohort of C9orf72 expansion ca...
Autores principales: | Llibre‐Guerra, Jorge J., Lee, Suzee E., Suemoto, Claudia K., Ehrenberg, Alexander J., Kovacs, Gabor G., Karydas, Anna, Staffaroni, Adam, Franca Resende, Elisa De Paula, Kim, Eun‐Joo, Hwang, Ji‐Hye, Ramos, Eliana Marisa, Wojta, Kevin J., Pasquini, Lorenzo, Pang, Shirley Yin‐Yu, Spina, Salvatore, Allen, Isabel E., Kramer, Joel, Miller, Bruce L., Seeley, William W., Grinberg, Lea T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946775/ https://www.ncbi.nlm.nih.gov/pubmed/33314436 http://dx.doi.org/10.1111/bpa.12924 |
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