Cargando…

Gastroprotective Effect of Sinapic Acid on Ethanol-Induced Gastric Ulcers in Rats: Involvement of Nrf2/HO-1 and NF-κB Signaling and Antiapoptotic Role

Background: In the current study, we evaluated the therapeutic potential of sinapic acid (SA) in terms of the mechanism underlying its gastroprotective action against ethanol-induced gastric ulcers in rats. Methods: These effects were examined through gross macroscopic evaluation of the stomach cavi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Raish, Mohammad, Shahid, Mudassar, Bin Jardan, Yousef A., Ansari, Mushtaq Ahmad, Alkharfy, Khalid M., Ahad, Abdul, Abdelrahman, Ibrahim Abdelsalam, Ahmad, Ajaz, Al-Jenoobi, Fahad I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946842/ https://www.ncbi.nlm.nih.gov/pubmed/33716749 http://dx.doi.org/10.3389/fphar.2021.622815

Ejemplares similares

Sinapic Acid Ameliorates Acetic Acid-Induced Ulcerative Colitis in Rats by Suppressing Inflammation, Oxidative Stress, and Apoptosis
por: Shahid, Mudassar, et al.
Publicado: (2022)

Herb-drug interaction: Effect of sinapic acid on the pharmacokinetics of dasatinib in rats
por: Shahid, Mudassar, et al.
Publicado: (2023)

Sinapic acid alleviates 5-fluorouracil-induced nephrotoxicity in rats via Nrf2/HO-1 signalling
por: Ahmad Ansari, Mushtaq, et al.
Publicado: (2023)

Sinapic Acid Ameliorates Oxidative Stress, Inflammation, and Apoptosis in Acute Doxorubicin-Induced Cardiotoxicity via the NF-κB-Mediated Pathway
por: Bin Jardan, Yousef A., et al.
Publicado: (2020)

Preparation and Characterization of Transethosome Formulation for the Enhanced Delivery of Sinapic Acid
por: Bin Jardan, Yousef A., et al.
Publicado: (2023)

Eudragit-Coated Sporopollenin Exine Microcapsules (SEMC) of Phoenix dactylifera L. of 5-Fluorouracil for Colon-Specific Drug Delivery
por: Raish, Mohammad, et al.
Publicado: (2021)

Effects of Apigenin on Pharmacokinetics of Dasatinib and Probable Interaction Mechanism
por: Raish, Mohammad, et al.
Publicado: (2023)

Effect of sinapic acid on aripiprazole pharmacokinetics in rats: Possible food drug interaction
por: Raish, Mohammad, et al.
Publicado: (2018)

Sinapic acid ameliorates D-galactosamine/lipopolysaccharide-induced fulminant hepatitis in rats: Role of nuclear factor erythroid-related factor 2/heme oxygenase-1 pathways
por: Ansari, Mushtaq Ahmad, et al.
Publicado: (2021)

Quality assessment of different brands of atorvastatin tablets available in Riyadh, Saudi Arabia
por: AlMuhsin, Ali, et al.
Publicado: (2022)

Cinnamon modulates the pharmacodynamic & pharmacokinetic of amlodipine in hypertensive rats
por: Abdelrahman, Ibrahim Abdelsalam, et al.
Publicado: (2023)

Thermodynamic Solubility Profile of Temozolomide in Different Commonly Used Pharmaceutical Solvents
por: Ahad, Abdul, et al.
Publicado: (2022)

Assessment of glibenclamide pharmacokinetics in poloxamer 407-induced hyperlipidemic rats
por: Bin Jardan, Yousef A., et al.
Publicado: (2021)

Formulation and characterization of eprosartan mesylate and β-cyclodextrin inclusion complex prepared by microwave technology
por: Ahad, Abdul, et al.
Publicado: (2022)

Changes in Pharmacokinetics and Pharmacodynamics of Losartan in Experimental Diseased Rats Treated with Curcuma longa and Lepidium sativum
por: Ahad, Abdul, et al.
Publicado: (2022)

Hepatoprotective activity of Lepidium sativum seeds against D-galactosamine/lipopolysaccharide induced hepatotoxicity in animal model
por: Raish, Mohammad, et al.
Publicado: (2016)

Delivery of Insulin via Skin Route for the Management of Diabetes Mellitus: Approaches for Breaching the Obstacles
por: Ahad, Abdul, et al.
Publicado: (2021)

Potential pharmacodynamic and pharmacokinetic interactions of Nigella Sativa and Trigonella Foenum-graecum with losartan in L-NAME induced hypertensive rats
por: Ahad, Abdul, et al.
Publicado: (2020)

Effects of garden cress, fenugreek and black seed on the pharmacodynamics of metoprolol: an herb-drug interaction study in rats with hypertension
por: Bin Jardan, Yousef A., et al.
Publicado: (2021)

The potential role of thymoquinone in preventing the cardiovascular complications of COVID-19
por: Ahmad, Ajaz, et al.
Publicado: (2021)

Identification of Doxorubicin as Repurposing Inhibitory Drug for MERS-CoV PLpro
por: Alaofi, Ahmed L., et al.
Publicado: (2022)

Sinapic Acid Ameliorates the Progression of Streptozotocin (STZ)-Induced Diabetic Nephropathy in Rats via NRF2/HO-1 Mediated Pathways
por: Alaofi, Ahmed L.
Publicado: (2020)

Thymoquinone modulates the expression of sepsis-related microRNAs in a CLP model
por: Alkharfy, Khalid M., et al.
Publicado: (2022)

Instantaneous Sinapisms
Publicado: (1876)

Gender effect on the pharmacokinetics of thymoquinone: Preclinical investigation and in silico modeling in male and female rats
por: Ahmad, Ajaz, et al.
Publicado: (2020)

Systemic delivery of β-blockers via transdermal route for hypertension
por: Ahad, Abdul, et al.
Publicado: (2015)

Evaluation of the in vivo genotoxicity of liposomal formulation for delivering anticancer estrogenic derivative (ESC8) in a mouse model
por: Ahmad, Ajaz, et al.
Publicado: (2019)

Sinapisms to the Mammæ for Suppression of the Menses
por: Phelp, O. J.
Publicado: (1852)

Antiapoptotic and Antioxidant Properties of Orthosiphon stamineus Benth (Cat's Whiskers): Intervention in the Bcl-2-Mediated Apoptotic Pathway
por: Abdelwahab, Siddig Ibrahim, et al.
Publicado: (2011)

Gastroprotective mechanism of modified lvdou gancao decoction on ethanol-induced gastric lesions in mice: Involvement of Nrf-2/HO-1/NF-κB signaling pathway
por: Xie, Lei, et al.
Publicado: (2022)

Formulation and characterization of novel soft nanovesicles for enhanced transdermal delivery of eprosartan mesylate
por: Ahad, Abdul, et al.
Publicado: (2017)

Sinapic Acid and Sinapate Esters in Brassica: Innate Accumulation, Biosynthesis, Accessibility via Chemical Synthesis or Recovery From Biomass, and Biological Activities
por: Nguyen, V. P. Thinh, et al.
Publicado: (2021)

Alleviation of Cartilage Destruction by Sinapic Acid in Experimental Osteoarthritis
por: Cai, Dawei, et al.
Publicado: (2019)

Saudi Arabia, pharmacists and COVID-19 pandemic
por: Ahmad, Ajaz, et al.
Publicado: (2020)

Flavonoids with Gastroprotective Activity
por: de Lira Mota, Kelly Samara, et al.
Publicado: (2009)

GC-MS Analysis and Gastroprotective Evaluations of Crude Extracts, Isolated Saponins, and Essential Oil from Polygonum hydropiper L.
por: Ayaz, Muhammad, et al.
Publicado: (2017)

The protective effect of sinapic acid in osteoarthritis: In vitro and in vivo studies
por: Li, Xiaobin, et al.
Publicado: (2019)

Sinapine, but not sinapic acid, counteracts mitochondrial oxidative stress in cardiomyocytes
por: Boulghobra, Doria, et al.
Publicado: (2020)

Direct structural observation of ultrafast photoisomerization dynamics in sinapate esters
por: Abiola, Temitope T., et al.
Publicado: (2022)

An Antiapoptotic Neuroprotective Role for Neuroglobin
por: Brittain, Thomas, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_6mv7itf53ol2pvmfcraqt52k34