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HNRNPA1-mediated exosomal sorting of miR-483-5p out of renal tubular epithelial cells promotes the progression of diabetic nephropathy-induced renal interstitial fibrosis

Diabetic nephropathy (DN) is a serious complication in type 1 and type 2 diabetes, and renal interstitial fibrosis plays a key role in DN progression. Here, we aimed to probe into the role and potential mechanism of miR-483-5p in DN-induced renal interstitial fibrosis. In this study, we corroborated...

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Detalles Bibliográficos
Autores principales: Liu, DongWei, Liu, FengXun, Li, ZhengYong, Pan, ShaoKang, Xie, JunWei, Zhao, ZiHao, Liu, ZhenJie, Zhang, JiaHui, Liu, ZhangSuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946926/
https://www.ncbi.nlm.nih.gov/pubmed/33692334
http://dx.doi.org/10.1038/s41419-021-03460-x