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Parainfluenza Virus 5 Priming Followed by SIV/HIV Virus-Like-Particle Boosting Induces Potent and Durable Immune Responses in Nonhuman Primates

The search for a preventive vaccine against HIV infection remains an ongoing challenge, indicating the need for novel approaches. Parainfluenza virus 5 (PIV5) is a paramyxovirus replicating in the upper airways that is not associated with any animal or human pathology. In animal models, PIV5-vectore...

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Detalles Bibliográficos
Autores principales: Xiao, Peng, Dienger-Stambaugh, Krista, Chen, Xuemin, Wei, Huiling, Phan, Shannon, Beavis, Ashley C., Singh, Karnail, Adhikary, Nihar R. Deb, Tiwari, Pooja, Villinger, Francois, He, Biao, Spearman, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946978/
https://www.ncbi.nlm.nih.gov/pubmed/33717130
http://dx.doi.org/10.3389/fimmu.2021.623996