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Deletion of Mea6 in Cerebellar Granule Cells Impairs Synaptic Development and Motor Performance
The cerebellum is conceptualized as a processor of complex movements. Many diseases with gene-targeted mutations, including Fahr’s disease associated with the loss-of-function mutation of meningioma expressed antigen 6 (Mea6), exhibit cerebellar malformations, and abnormal motor behaviors. We previo...
Autores principales: | Wang, Xin-Tai, Zhou, Lin, Cai, Xin-Yu, Xu, Fang-Xiao, Xu, Zhi-Heng, Li, Xiang-Yao, Shen, Ying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946997/ https://www.ncbi.nlm.nih.gov/pubmed/33718348 http://dx.doi.org/10.3389/fcell.2020.627146 |
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