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Leptin Receptor q223r Polymorphism Influences Clostridioides difficile Infection-Induced Neutrophil CXCR2 Expression in an Interleukin-1β Dependent Manner

Neutrophils are key first-responders in the innate immune response to C. difficile infection (CDI) and play a central role in disease pathogenesis. Studies have clearly shown that tissue neutrophil numbers need to be tightly regulated for optimal CDI outcomes: while excessive colonic neutrophilia is...

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Detalles Bibliográficos
Autores principales:	Horrigan, Olivia, Jose, Shinsmon, Mukherjee, Anindita, Sharma, Divya, Huber, Alexander, Madan, Rajat
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cellular and Infection Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946998/ https://www.ncbi.nlm.nih.gov/pubmed/33718269 http://dx.doi.org/10.3389/fcimb.2021.619192

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