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Pin1 Promotes NLRP3 Inflammasome Activation by Phosphorylation of p38 MAPK Pathway in Septic Shock

Pin1 is the only known peptidyl-prolyl cis-trans isomerase (PPIase) that can specifically recognize and isomerize the phosphorylated Serine/Threonine-Proline (pSer/Thr-Pro) motif, change the conformation of proteins through protein phosphorylation, thus regulate various cellular processes in the bod...

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Detalles Bibliográficos
Autores principales: Dong, Ruijie, Xue, Zhenyi, Fan, Guangyue, Zhang, Na, Wang, Chengzhi, Li, Guangliang, Da, Yurong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7947244/
https://www.ncbi.nlm.nih.gov/pubmed/33717117
http://dx.doi.org/10.3389/fimmu.2021.620238

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