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Pin1 Promotes NLRP3 Inflammasome Activation by Phosphorylation of p38 MAPK Pathway in Septic Shock
Pin1 is the only known peptidyl-prolyl cis-trans isomerase (PPIase) that can specifically recognize and isomerize the phosphorylated Serine/Threonine-Proline (pSer/Thr-Pro) motif, change the conformation of proteins through protein phosphorylation, thus regulate various cellular processes in the bod...
Autores principales: | Dong, Ruijie, Xue, Zhenyi, Fan, Guangyue, Zhang, Na, Wang, Chengzhi, Li, Guangliang, Da, Yurong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7947244/ https://www.ncbi.nlm.nih.gov/pubmed/33717117 http://dx.doi.org/10.3389/fimmu.2021.620238 |
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