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STEMI associated with SARS-CoV-2 infection and the use of ECMO as a potential therapeutic approach in addition to the PCI
A 55-year-old male presented to the emergency department with the complaints of chest pain that started 4 h before presentation. Pain was located over the anterior chest, 5 out of 10 intensity, with radiation to the left arm. Chest x-ray on admission showed severe diffuse bilateral pulmonary infiltr...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7947272/ https://www.ncbi.nlm.nih.gov/pubmed/33732477 http://dx.doi.org/10.1093/omcr/omaa148 |
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author | Rahman, Tanvir Alayo, Quazim A Chaudhary, Sibgha G Moghadam, Reihaneh C German, Matthew L Ettinger, Neil A Leidenfrost, Jeremy E Cranston-D'amato, Hope A Rinder, Morton R Donnelly, Julianne E |
author_facet | Rahman, Tanvir Alayo, Quazim A Chaudhary, Sibgha G Moghadam, Reihaneh C German, Matthew L Ettinger, Neil A Leidenfrost, Jeremy E Cranston-D'amato, Hope A Rinder, Morton R Donnelly, Julianne E |
author_sort | Rahman, Tanvir |
collection | PubMed |
description | A 55-year-old male presented to the emergency department with the complaints of chest pain that started 4 h before presentation. Pain was located over the anterior chest, 5 out of 10 intensity, with radiation to the left arm. Chest x-ray on admission showed severe diffuse bilateral pulmonary infiltrates concerning for COVID-19 pneumonia. Electrocardiogram showed inferior and lateral ST-segment elevation compatible with acute inferolateral myocardial infarction. Successful percutaneous coronary intervention (PCI) of the proximal and mid-right coronary artery using the balloon angioplasty and drug-eluting stent was performed. Post-PCI stenosis was 0% with a thrombolysis in myocardial infarction (TIMI) flow of 3. Five-day course of azithromycin and hydroxychloroquine was completed with no improvement overall. Patient received two doses of 400 mg of tocilizumab intravenously on hospital days 5 (HD#5) and #6. The patient was proned, on FiO(2) 100%, PEEP 15 cm H(2)O, on epoprostenol sodium and paralytics and eventually received venovenous ECMO, which improved outcome. |
format | Online Article Text |
id | pubmed-7947272 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-79472722021-03-16 STEMI associated with SARS-CoV-2 infection and the use of ECMO as a potential therapeutic approach in addition to the PCI Rahman, Tanvir Alayo, Quazim A Chaudhary, Sibgha G Moghadam, Reihaneh C German, Matthew L Ettinger, Neil A Leidenfrost, Jeremy E Cranston-D'amato, Hope A Rinder, Morton R Donnelly, Julianne E Oxf Med Case Reports Case Report A 55-year-old male presented to the emergency department with the complaints of chest pain that started 4 h before presentation. Pain was located over the anterior chest, 5 out of 10 intensity, with radiation to the left arm. Chest x-ray on admission showed severe diffuse bilateral pulmonary infiltrates concerning for COVID-19 pneumonia. Electrocardiogram showed inferior and lateral ST-segment elevation compatible with acute inferolateral myocardial infarction. Successful percutaneous coronary intervention (PCI) of the proximal and mid-right coronary artery using the balloon angioplasty and drug-eluting stent was performed. Post-PCI stenosis was 0% with a thrombolysis in myocardial infarction (TIMI) flow of 3. Five-day course of azithromycin and hydroxychloroquine was completed with no improvement overall. Patient received two doses of 400 mg of tocilizumab intravenously on hospital days 5 (HD#5) and #6. The patient was proned, on FiO(2) 100%, PEEP 15 cm H(2)O, on epoprostenol sodium and paralytics and eventually received venovenous ECMO, which improved outcome. Oxford University Press 2021-03-08 /pmc/articles/PMC7947272/ /pubmed/33732477 http://dx.doi.org/10.1093/omcr/omaa148 Text en © The Author(s) 2021. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Case Report Rahman, Tanvir Alayo, Quazim A Chaudhary, Sibgha G Moghadam, Reihaneh C German, Matthew L Ettinger, Neil A Leidenfrost, Jeremy E Cranston-D'amato, Hope A Rinder, Morton R Donnelly, Julianne E STEMI associated with SARS-CoV-2 infection and the use of ECMO as a potential therapeutic approach in addition to the PCI |
title | STEMI associated with SARS-CoV-2 infection and the use of ECMO as a potential therapeutic approach in addition to the PCI |
title_full | STEMI associated with SARS-CoV-2 infection and the use of ECMO as a potential therapeutic approach in addition to the PCI |
title_fullStr | STEMI associated with SARS-CoV-2 infection and the use of ECMO as a potential therapeutic approach in addition to the PCI |
title_full_unstemmed | STEMI associated with SARS-CoV-2 infection and the use of ECMO as a potential therapeutic approach in addition to the PCI |
title_short | STEMI associated with SARS-CoV-2 infection and the use of ECMO as a potential therapeutic approach in addition to the PCI |
title_sort | stemi associated with sars-cov-2 infection and the use of ecmo as a potential therapeutic approach in addition to the pci |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7947272/ https://www.ncbi.nlm.nih.gov/pubmed/33732477 http://dx.doi.org/10.1093/omcr/omaa148 |
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