Tropoelastin and Elastin Assembly

Elastic fibers are an important component of the extracellular matrix, providing stretch, resilience, and cell interactivity to a broad range of elastic tissues. Elastin makes up the majority of elastic fibers and is formed by the hierarchical assembly of its monomer, tropoelastin. Our understanding...

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Autores principales: Ozsvar, Jazmin, Yang, Chengeng, Cain, Stuart A., Baldock, Clair, Tarakanova, Anna, Weiss, Anthony S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7947355/
https://www.ncbi.nlm.nih.gov/pubmed/33718344
http://dx.doi.org/10.3389/fbioe.2021.643110
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author Ozsvar, Jazmin
Yang, Chengeng
Cain, Stuart A.
Baldock, Clair
Tarakanova, Anna
Weiss, Anthony S.
author_facet Ozsvar, Jazmin
Yang, Chengeng
Cain, Stuart A.
Baldock, Clair
Tarakanova, Anna
Weiss, Anthony S.
author_sort Ozsvar, Jazmin
collection PubMed
description Elastic fibers are an important component of the extracellular matrix, providing stretch, resilience, and cell interactivity to a broad range of elastic tissues. Elastin makes up the majority of elastic fibers and is formed by the hierarchical assembly of its monomer, tropoelastin. Our understanding of key aspects of the assembly process have been unclear due to the intrinsic properties of elastin and tropoelastin that render them difficult to study. This review focuses on recent developments that have shaped our current knowledge of elastin assembly through understanding the relationship between tropoelastin’s structure and function.
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spelling pubmed-79473552021-03-12 Tropoelastin and Elastin Assembly Ozsvar, Jazmin Yang, Chengeng Cain, Stuart A. Baldock, Clair Tarakanova, Anna Weiss, Anthony S. Front Bioeng Biotechnol Bioengineering and Biotechnology Elastic fibers are an important component of the extracellular matrix, providing stretch, resilience, and cell interactivity to a broad range of elastic tissues. Elastin makes up the majority of elastic fibers and is formed by the hierarchical assembly of its monomer, tropoelastin. Our understanding of key aspects of the assembly process have been unclear due to the intrinsic properties of elastin and tropoelastin that render them difficult to study. This review focuses on recent developments that have shaped our current knowledge of elastin assembly through understanding the relationship between tropoelastin’s structure and function. Frontiers Media S.A. 2021-02-25 /pmc/articles/PMC7947355/ /pubmed/33718344 http://dx.doi.org/10.3389/fbioe.2021.643110 Text en Copyright © 2021 Ozsvar, Yang, Cain, Baldock, Tarakanova and Weiss. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Bioengineering and Biotechnology
Ozsvar, Jazmin
Yang, Chengeng
Cain, Stuart A.
Baldock, Clair
Tarakanova, Anna
Weiss, Anthony S.
Tropoelastin and Elastin Assembly
title Tropoelastin and Elastin Assembly
title_full Tropoelastin and Elastin Assembly
title_fullStr Tropoelastin and Elastin Assembly
title_full_unstemmed Tropoelastin and Elastin Assembly
title_short Tropoelastin and Elastin Assembly
title_sort tropoelastin and elastin assembly
topic Bioengineering and Biotechnology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7947355/
https://www.ncbi.nlm.nih.gov/pubmed/33718344
http://dx.doi.org/10.3389/fbioe.2021.643110
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AT tarakanovaanna tropoelastinandelastinassembly
AT weissanthonys tropoelastinandelastinassembly

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