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Cell-free DNA from cerebrospinal fluid can be used to detect the EGFR mutation status of lung adenocarcinoma patients with central nervous system metastasis

BACKGROUND: EGFR tyrosine kinase inhibitors (TKIs) have revolutionized the therapeutic approach for EGFR mutated patients. However, acquired resistance to EGFR-TKI therapy is unavoidable. Repeat biopsy cannot be used, and peripheral blood detection shows a low positive rate in cases of brain-only di...

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Detalles Bibliográficos
Autores principales:	Liu, Yang, Yang, Sen, Zhao, Jiuzhou, He, Zhen, Ma, Jie, Guo, Yongjun, Wang, Wei, Yoshizawa, Akihiko, Prelaj, Arsela, Tiseo, Marcello, Normanno, Nicola, Van Schil, Paul E., Wang, Qiming, Yang, Xiaopeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7947414/ https://www.ncbi.nlm.nih.gov/pubmed/33718032 http://dx.doi.org/10.21037/tlcr-21-62

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