Downregulation of PARVA promotes metastasis by modulating integrin-linked kinase activity and regulating MAPK/ERK and MLC2 signaling in prostate cancer

BACKGROUND: Metastasis is the predominant cause of mortality in prostate cancer (PCa); however, the underlying mechanisms are largely uncharted. Here, we found that Parvin alpha (PARVA) is downregulated in PCa and its loss is associated with clinical metastasis. We further explored the mechanistic b...

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Detalles Bibliográficos
Autores principales: Huang, Cong, Shen, Qi, Song, Gang, He, Shiming, Zhou, Liqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7947443/
https://www.ncbi.nlm.nih.gov/pubmed/33718092
http://dx.doi.org/10.21037/tau-21-108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7947443/
https://www.ncbi.nlm.nih.gov/pubmed/33718092
http://dx.doi.org/10.21037/tau-21-108

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