Cargando…

Fragile Gene WWOX Guides TFAP2A/TFAP2C-Dependent Actions Against Tumor Progression in Grade II Bladder Cancer

INTRODUCTION: The presence of common fragile sites is associated with no-accidental chromosomal instability which occurs prior to carcinogenesis. The WWOX gene spans the second most active fragile site: FRA16D. Chromosomal breakage at this site is more common in bladder cancer patients who are tobac...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kołat, Damian, Kałuzińska, Żaneta, Bednarek, Andrzej K., Płuciennik, Elżbieta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7947623/ https://www.ncbi.nlm.nih.gov/pubmed/33718178 http://dx.doi.org/10.3389/fonc.2021.621060

Ejemplares similares

Corrigendum: Fragile Gene WWOX Guides TFAP2A/TFAP2C-Dependent Actions Against Tumor Progression in Grade II Bladder Cancer
por: Kołat, Damian, et al.
Publicado: (2021)

WWOX Loses the Ability to Regulate Oncogenic AP-2γ and Synergizes with Tumor Suppressor AP-2α in High-Grade Bladder Cancer
por: Kołat, Damian, et al.
Publicado: (2021)

Determination of WWOX Function in Modulating Cellular Pathways Activated by AP-2α and AP-2γ Transcription Factors in Bladder Cancer
por: Kołat, Damian, et al.
Publicado: (2022)

LINC01137/miR-186-5p/WWOX: a novel axis identified from WWOX-related RNA interactome in bladder cancer
por: Kołat, Damian, et al.
Publicado: (2023)

PLEK2, RRM2, GCSH: A Novel WWOX-Dependent Biomarker Triad of Glioblastoma at the Crossroads of Cytoskeleton Reorganization and Metabolism Alterations
por: Kałuzińska, Żaneta, et al.
Publicado: (2021)

In vitro and in silico assessment of the effect of WWOX expression on invasiveness pathways associated with AP-2 transcription factors in bladder cancer
por: Kałuzińska, Żaneta, et al.
Publicado: (2021)

Antineoplastic Nature of WWOX in Glioblastoma Is Mainly a Consequence of Reduced Cell Viability and Invasion
por: Kałuzińska-Kołat, Żaneta, et al.
Publicado: (2023)

Molecular landscapes of glioblastoma cell lines revealed a group of patients that do not benefit from WWOX tumor suppressor expression
por: Kałuzińska-Kołat, Żaneta, et al.
Publicado: (2023)

The biological characteristics of transcription factors AP-2α and AP-2γ and their importance in various types of cancers
por: Kołat, Damian, et al.
Publicado: (2019)

Prognostic significance of AP-2α/γ targets as cancer therapeutics
por: Kołat, Damian, et al.
Publicado: (2022)

MicroRNAs: Their Role in Metastasis, Angiogenesis, and the Potential for Biomarker Utility in Bladder Carcinomas
por: Hammouz, Raneem Y., et al.
Publicado: (2021)

Functional genomics of AP-2α and AP-2γ in cancers: in silico study
por: Kołat, Damian, et al.
Publicado: (2020)

Delineating the glioblastoma stemness by genes involved in cytoskeletal rearrangements and metabolic alterations
por: Kałuzińska-Kołat, Żaneta, et al.
Publicado: (2023)

WWOX Tumor Suppressor Gene in Breast Cancer, a Historical Perspective and Future Directions
por: Pospiech, Karolina, et al.
Publicado: (2018)

AP-2δ Is the Most Relevant Target of AP-2 Family-Focused Cancer Therapy and Affects Genome Organization
por: Kołat, Damian, et al.
Publicado: (2022)

Distinct Activities of Tfap2A and Tfap2B in the Specification of GABAergic Interneurons in the Developing Cerebellum
por: Zainolabidin, Norliyana, et al.
Publicado: (2017)

Functional Divergence of Mammalian TFAP2a and TFAP2b Transcription Factors for Bidirectional Sleep Control
por: Hu, Yang, et al.
Publicado: (2020)

Identification of functional TFAP2A and SP1 binding sites in new TFAP2A-modulated genes
por: Orso, Francesca, et al.
Publicado: (2010)

TFAP2B mutation and dental anomalies
por: Tanasubsinn, Natchaya, et al.
Publicado: (2017)

TfAP-2 is required for night sleep in Drosophila
por: Kucherenko, Mariya M., et al.
Publicado: (2016)

TFAP2 transcription factors are regulators of lipid droplet biogenesis
por: Scott, Cameron C, et al.
Publicado: (2018)

TFAP2 paralogs regulate melanocyte differentiation in parallel with MITF
por: Seberg, Hannah E., et al.
Publicado: (2017)

Alternating expression levels of WWOX tumor suppressor and cancer-related genes in patients with bladder cancer
por: PŁUCIENNIK, ELŻBIETA, et al.
Publicado: (2014)

Increased expression of transcription factor TFAP2α correlates with chemosensitivity in advanced bladder cancer
por: Nordentoft, Iver, et al.
Publicado: (2011)

The WWOX gene in brain development and pathology
por: Kośla, K, et al.
Publicado: (2020)

Expression of Human Frataxin Is Regulated by Transcription Factors SRF and TFAP2
por: Li, Kuanyu, et al.
Publicado: (2010)

Tfap2b acts in GABAergic neurons to control sleep in mice
por: Hu, Yang, et al.
Publicado: (2023)

TFAP2A potentiates lung adenocarcinoma metastasis by a novel miR-16 family/TFAP2A/PSG9/TGF-β signaling pathway
por: Xiong, Yanlu, et al.
Publicado: (2021)

Pyroptosis-related signatures in bladder cancer prognosis and treatment—are we there yet?
por: Kołat, Damian, et al.
Publicado: (2022)

The artificial oxygen carrier erythrocruorin—characteristics and potential significance in medicine
por: Kruczkowska, Weronika, et al.
Publicado: (2023)

Exosomes as carriers transporting long non-coding RNAs: Molecular characteristics and their function in cancer
por: Kołat, Damian, et al.
Publicado: (2019)

The WWOX/HIF1A Axis Downregulation Alters Glucose Metabolism and Predispose to Metabolic Disorders
por: Baryła, Izabela, et al.
Publicado: (2022)

Alternative TFAP2A isoforms have distinct activities in breast cancer
por: Berlato, Chiara, et al.
Publicado: (2011)

TFAP2C Governs the Luminal Epithelial Phenotype in Mammary Development and Carcinogenesis
por: Cyr, Anthony R, et al.
Publicado: (2014)

TFAP2C regulates transcription in human naive pluripotency by opening enhancers
por: Pastor, William A., et al.
Publicado: (2018)

Overexpression of Tfap2a in Mouse Oocytes Impaired Spindle and Chromosome Organization
por: Lin, Juan, et al.
Publicado: (2022)

Molecular analysis of WWOX expression correlation with proliferation and apoptosis in glioblastoma multiforme
por: Kosla, Katarzyna, et al.
Publicado: (2010)

The WWOX Gene Influences Cellular Pathways in the Neuronal Differentiation of Human Neural Progenitor Cells
por: Kośla, Katarzyna, et al.
Publicado: (2019)

WWOX expression in colorectal cancer—a real-time quantitative RT-PCR study
por: Żelazowski, Maciej Jakub, et al.
Publicado: (2011)

TGFα-EGFR pathway in breast carcinogenesis, association with WWOX expression and estrogen activation
por: Pospiech, Karolina, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_uba33cjgrbtfm36pmvafb8gefb