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EZH2-miRNA Positive Feedback Promotes Tumor Growth in Ovarian Cancer

Enhancer of zester homolog 2 (EZH2), a histone methyl transferase that mediates H3K27me3 through polycomb repressive complex 2 (PRC2), is overexpressed in ovarian cancer and promotes malignant proliferation. However, the underlying mechanism of maintaining high EZH2 expression remains elusive. Here...

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Detalles Bibliográficos
Autores principales:	Liu, Ting, Cai, Jian, Cai, Jing, Wang, Zehua, Cai, Liqiong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7947696/ https://www.ncbi.nlm.nih.gov/pubmed/33718109 http://dx.doi.org/10.3389/fonc.2020.608393

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