Cargando…
The Role of EBV-Encoded LMP1 in the NPC Tumor Microenvironment: From Function to Therapy
Nasopharyngeal carcinoma (NPC) is closely associated with Epstein-Barr virus (EBV) infection. It is also characterized by heavy infiltration with non-malignant leucocytes. The EBV-encoded latent membrane protein 1 (LMP1) is believed to play an important role in NPC pathogenesis by virtue of its abil...
Autores principales: | Lo, Angela Kwok-Fung, Dawson, Christopher W., Lung, Hong Lok, Wong, Ka-Leung, Young, Lawrence S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7947715/ https://www.ncbi.nlm.nih.gov/pubmed/33718235 http://dx.doi.org/10.3389/fonc.2021.640207 |
Ejemplares similares
-
The Therapeutic Potential of Targeting BARF1 in EBV-Associated Malignancies
por: Lo, Angela Kwok-Fung, et al.
Publicado: (2020) -
The EBV-Encoded Oncoprotein, LMP1, Recruits and Transforms Fibroblasts via an ERK-MAPK-Dependent Mechanism
por: Davis, Alexandra M, et al.
Publicado: (2021) -
The EBV-encoded Latent Membrane Proteins, LMP2A and LMP2B, Limit the Actions of Interferon by Targeting Interferon Receptors for Degradation
por: Shah, Khilan M., et al.
Publicado: (2009) -
Activation of sterol regulatory element‐binding protein 1 (SREBP1)‐mediated lipogenesis by the Epstein–Barr virus‐encoded latent membrane protein 1 (LMP1) promotes cell proliferation and progression of nasopharyngeal carcinoma
por: Lo, Angela Kwok‐Fung, et al.
Publicado: (2018) -
Upregulation of Id1 by Epstein-Barr Virus-encoded LMP1 confers resistance to TGFβ-mediated growth inhibition
por: Lo, Angela KF, et al.
Publicado: (2010)