Cargando…

Inflammatory Determinants of Differential Tuberculosis Risk in Pre-Adolescent Children and Young Adults

The risk of progression from Mycobacterium tuberculosis (M.tb) infection to active tuberculosis (TB) disease varies markedly with age. TB disease is significantly less likely in pre-adolescent children above 4 years of age than in very young children or post-pubescent adolescents and young adults. W...

Descripción completa

Detalles Bibliográficos
Autores principales:	Baguma, Richard, Mbandi, Stanley Kimbung, Rodo, Miguel J., Erasmus, Mzwandile, Day, Jonathan, Makhethe, Lebohang, de Kock, Marwou, van Rooyen, Michele, Stone, Lynnett, Bilek, Nicole, Steyn, Marcia, Africa, Hadn, Darboe, Fatoumatta, Chegou, Novel N., Tromp, Gerard, Walzl, Gerhard, Hatherill, Mark, Penn-Nicholson, Adam, Scriba, Thomas J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7947716/ https://www.ncbi.nlm.nih.gov/pubmed/33717192 http://dx.doi.org/10.3389/fimmu.2021.639965

Ejemplares similares

Application of a whole blood mycobacterial growth inhibition assay to study immunity against Mycobacterium tuberculosis in a high tuberculosis burden population
por: Baguma, Richard, et al.
Publicado: (2017)

Plasma Type I IFN Protein Concentrations in Human Tuberculosis
por: Llibre, Alba, et al.
Publicado: (2019)

Detection of Tuberculosis Recurrence, Diagnosis and Treatment Response by a Blood Transcriptomic Risk Signature in HIV-Infected Persons on Antiretroviral Therapy
por: Darboe, Fatoumatta, et al.
Publicado: (2019)

Host blood transcriptomic biomarkers of tuberculosis disease in people living with HIV: a systematic review protocol
por: Mendelsohn, Simon C, et al.
Publicado: (2021)

RISK6, a 6-gene transcriptomic signature of TB disease risk, diagnosis and treatment response
por: Penn-Nicholson, Adam, et al.
Publicado: (2020)

Prospective multicentre head-to-head validation of host blood transcriptomic biomarkers for pulmonary tuberculosis by real-time PCR
por: Mendelsohn, Simon C., et al.
Publicado: (2022)

Blood transcriptional signatures for tuberculosis testing
por: Mendelsohn, Simon C, et al.
Publicado: (2020)

Longitudinal Dynamics of a Blood Transcriptomic Signature of Tuberculosis
por: Mulenga, Humphrey, et al.
Publicado: (2021)

Diagnostic Accuracy of Early Secretory Antigenic Target-6–Free Interferon-gamma Release Assay Compared to QuantiFERON-TB Gold In-tube
por: Nemes, Elisa, et al.
Publicado: (2019)

Multidimensional analyses reveal modulation of adaptive and innate immune subsets by tuberculosis vaccines
por: Rozot, Virginie, et al.
Publicado: (2020)

Performance of host blood transcriptomic signatures for diagnosing and predicting progression to tuberculosis disease in HIV-negative adults and adolescents: a systematic review protocol
por: Mulenga, Humphrey, et al.
Publicado: (2019)

The effect of host factors on discriminatory performance of a transcriptomic signature of tuberculosis risk
por: Mulenga, Humphrey, et al.
Publicado: (2022)

Biomarker-guided tuberculosis preventive therapy (CORTIS): a randomised controlled trial
por: Scriba, Thomas J, et al.
Publicado: (2021)

Validation of a host blood transcriptomic biomarker for pulmonary tuberculosis in people living with HIV: a prospective diagnostic and prognostic accuracy study
por: Mendelsohn, Simon C, et al.
Publicado: (2021)

Evaluation of a transcriptomic signature of tuberculosis risk in combination with an interferon gamma release assay: A diagnostic test accuracy study
por: Mulenga, Humphrey, et al.
Publicado: (2022)

Clinical predictors of pulmonary tuberculosis among South African adults with HIV
por: Mendelsohn, Simon C., et al.
Publicado: (2022)

Performance of diagnostic and predictive host blood transcriptomic signatures for Tuberculosis disease: A systematic review and meta-analysis
por: Mulenga, Humphrey, et al.
Publicado: (2020)

Tuberculosis alters immune-metabolic pathways resulting in perturbed IL-1 responses
por: Llibre, Alba, et al.
Publicado: (2022)

PD-1 Expression on Mycobacterium tuberculosis-Specific CD4 T Cells Is Associated With Bacterial Load in Human Tuberculosis
por: Day, Cheryl L., et al.
Publicado: (2018)

Immune Profiling Enables Stratification of Patients With Active Tuberculosis Disease or Mycobacterium tuberculosis Infection
por: Duffy, Darragh, et al.
Publicado: (2020)

Tuberculous Meningitis: Pathogenesis, Immune Responses, Diagnostic Challenges, and the Potential of Biomarker-Based Approaches
por: Manyelo, Charles M., et al.
Publicado: (2021)

Host transcriptomic signatures of tuberculosis can predict immune reconstitution inflammatory syndrome in HIV patients
por: Mbandi, Stanley Kimbung, et al.
Publicado: (2022)

Sequential inflammatory processes define human progression from M. tuberculosis infection to tuberculosis disease
por: Scriba, Thomas J., et al.
Publicado: (2017)

Prevention of Infection with Mycobacterium tuberculosis by H4:IC31® Vaccination or BCG Revaccination in Adolescents
por: Nemes, Elisa, et al.
Publicado: (2018)

Suitability of saliva for Tuberculosis diagnosis: comparing with serum
por: Namuganga, Anna Ritah, et al.
Publicado: (2017)

Discovery and validation of a prognostic proteomic signature for tuberculosis progression: A prospective cohort study
por: Penn-Nicholson, Adam, et al.
Publicado: (2019)

Correction: Discovery and validation of a prognostic proteomic signature for tuberculosis progression: A prospective cohort study
por: Penn-Nicholson, Adam, et al.
Publicado: (2019)

Host markers in Quantiferon supernatants differentiate active TB from latent TB infection: preliminary report
por: Chegou, Novel N, et al.
Publicado: (2009)

The gut microbiome in tuberculosis susceptibility and treatment response: guilty or not guilty?
por: Eribo, Osagie A., et al.
Publicado: (2019)

An Archetypical Model for Engrafting Bacteroides fragilis into Conventional Mice Following Reproducible Antibiotic Conditioning of the Gut Microbiota
por: Eribo, Osagie A., et al.
Publicado: (2023)

Targeted Gene Expression Profiling of Human Myeloid Cells From Blood and Lung Compartments of Patients With Tuberculosis and Other Lung Diseases
por: Kotze, Leigh Ann, et al.
Publicado: (2022)

Effects of BCG vaccination on donor unrestricted T cells in two prospective cohort studies
por: Gela, Anele, et al.
Publicado: (2022)

Utility of Host Markers Detected in Quantiferon Supernatants for the Diagnosis of Tuberculosis in Children in a High-Burden Setting
por: Chegou, Novel N., et al.
Publicado: (2013)

Identification of novel host biomarkers in plasma as candidates for the immunodiagnosis of tuberculosis disease and monitoring of tuberculosis treatment response
por: Jacobs, Ruschca, et al.
Publicado: (2016)

A comparison of antigen-specific T cell responses induced by six novel tuberculosis vaccine candidates
por: Rodo, Miguel J., et al.
Publicado: (2019)

Diagnostic Potential of Novel Salivary Host Biomarkers as Candidates for the Immunological Diagnosis of Tuberculosis Disease and Monitoring of Tuberculosis Treatment Response
por: Jacobs, Ruschca, et al.
Publicado: (2016)

Potential of Host Serum Protein Biomarkers in the Diagnosis of Tuberculous Meningitis in Children
por: Manyelo, Charles M., et al.
Publicado: (2019)

Candidate Biomarkers to Distinguish Spinal Tuberculosis From Mechanical Back Pain in a Tuberculosis Endemic Setting
por: Mann, Theresa N., et al.
Publicado: (2021)

Potential population level impact on tuberculosis incidence of using an mRNA expression signature correlate-of-risk test to target tuberculosis preventive therapy
por: Sumner, Tom, et al.
Publicado: (2019)

Considerations for biomarker-targeted intervention strategies for tuberculosis disease prevention
por: Fiore-Gartland, Andrew, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_dlpcmhif0dlvf5t4l63uth445v