Cargando…

Extracellular Vesicles Derived From Adult and Fetal Bone Marrow Mesenchymal Stromal Cells Differentially Promote ex vivo Expansion of Hematopoietic Stem and Progenitor Cells

Recently, we and others have illustrated that extracellular vesicles (EVs) have the potential to support hematopoietic stem and progenitor cell (HSPC) expansion; however, the mechanism and processes responsible for the intercellular communication by EVs are still unknown. In the current study, we in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ghebes, Corina A., Morhayim, Jess, Kleijer, Marion, Koroglu, Merve, Erkeland, Stefan J., Hoogenboezem, Remco, Bindels, Eric, van Alphen, Floris P. J., van den Biggelaar, Maartje, Nolte, Martijn A., van der Eerden, Bram C. J., Braakman, Eric, Voermans, Carlijn, van de Peppel, Jeroen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Bioengineering and Biotechnology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7947881/ https://www.ncbi.nlm.nih.gov/pubmed/33718342 http://dx.doi.org/10.3389/fbioe.2021.640419

Ejemplares similares

Identification of osteolineage cell‐derived extracellular vesicle cargo implicated in hematopoietic support
por: Morhayim, Jess, et al.
Publicado: (2020)

Osteoblasts secrete miRNA-containing extracellular vesicles that enhance expansion of human umbilical cord blood cells
por: Morhayim, Jess, et al.
Publicado: (2016)

P318: LOSS OF SCARNA12 RESULTS IN ABERRANT SPLICING OF TARGET GENES AND DOWNREGULATION OF P53 IN B-CELL PRECURSOR ACUTE LYMPHOBLASTIC LEUKEMIA (BCP-ALL)
por: Verbeek, Martijn, et al.
Publicado: (2023)

Nuclear shape, protrusive behaviour and in vivo retention of human bone marrow mesenchymal stromal cells is controlled by Lamin-A/C expression
por: Dorland, Yvonne L., et al.
Publicado: (2019)

The Metastatic Bone Marrow Niche in Neuroblastoma: Altered Phenotype and Function of Mesenchymal Stromal Cells
por: Hochheuser, Caroline, et al.
Publicado: (2020)

Probing activation‐driven changes in coagulation factor IX by mass spectrometry
por: Freato, Nadia, et al.
Publicado: (2021)

Glucocorticoids induce differentiation of monocytes towards macrophages that share functional and phenotypical aspects with erythroblastic island macrophages
por: Heideveld, Esther, et al.
Publicado: (2018)

HSPB7 oppositely regulates human mesenchymal stromal cell-derived osteogenesis and adipogenesis
por: Zhang, Shuang, et al.
Publicado: (2023)

Tensin-3 is involved in osteogenic versus adipogenic fate of human bone marrow stromal cells
por: Zhang, Shuang, et al.
Publicado: (2023)

Defective AP-3-dependent VAMP8 trafficking impairs Weibel-Palade body exocytosis in Hermansky-Pudlak Syndrome type 2 blood outgrowth endothelial cells
por: Karampini, Ellie, et al.
Publicado: (2019)

Flow-induced Reorganization of Laminin-integrin Networks Within the Endothelial Basement Membrane Uncovered by Proteomics
por: Béguin, Eelke P., et al.
Publicado: (2020)

Interferon-Gamma Impairs Maintenance and Alters Hematopoietic Support of Bone Marrow Mesenchymal Stromal Cells
por: Goedhart, Marieke, et al.
Publicado: (2018)

Paracrine Signaling by Extracellular Vesicles via Osteoblasts
por: Morhayim, Jess, et al.
Publicado: (2016)

Two‐day‐treatment of Activin‐A leads to transient change in SV‐HFO osteoblast gene expression and reduction in matrix mineralization
por: Baroncelli, Marta, et al.
Publicado: (2019)

Identification of small molecules as novel anti-adipogenic compounds based on Connectivity Map
por: Zhang, Shuang, et al.
Publicado: (2022)

Memory CD8(+) T cells upregulate glycolysis and effector functions under limiting oxygen conditions
por: Beumer‐Chuwonpad, Ammarina, et al.
Publicado: (2022)

Multi-omics delineation of cytokine-induced endothelial inflammatory states
por: Groten, Stijn A., et al.
Publicado: (2023)

Rapid in vitro generation of bona fide exhausted CD8+ T cells is accompanied by Tcf7 promotor methylation
por: Zhao, Manzhi, et al.
Publicado: (2020)

Time-dependent regulation of cytokine production by RNA binding proteins defines T cell effector function
por: Popović, Branka, et al.
Publicado: (2023)

Hematopoietic stem and progenitor cells use podosomes to transcellularly cross the bone marrow endothelium
por: Rademakers, Timo, et al.
Publicado: (2020)

TGFBI Expressed by Bone Marrow Niche Cells and Hematopoietic Stem and Progenitor Cells Regulates Hematopoiesis
por: Klamer, Sofieke E., et al.
Publicado: (2018)

Alternative trafficking of Weibel‐Palade body proteins in CRISPR/Cas9‐engineered von Willebrand factor–deficient blood outgrowth endothelial cells
por: Schillemans, Maaike, et al.
Publicado: (2019)

Syntaxin 5 determines Weibel-Palade body size and von Willebrand factor secretion by controlling Golgi architecture
por: Kat, Marije, et al.
Publicado: (2022)

Human mesenchymal stromal cells in adhesion to cell‐derived extracellular matrix and titanium: Comparative kinome profile analysis
por: Baroncelli, Marta, et al.
Publicado: (2018)

The Rho-guanine nucleotide exchange factor Trio controls leukocyte transendothelial migration by promoting docking structure formation
por: van Rijssel, Jos, et al.
Publicado: (2012)

Inside-Out Regulation of ICAM-1 Dynamics in TNF-α-Activated Endothelium
por: van Buul, Jaap D., et al.
Publicado: (2010)

The Rho-GEF Trio regulates a novel pro-inflammatory pathway through the transcription factor Ets2
por: Van Rijssel, Jos, et al.
Publicado: (2013)

Hydroxychloroquine decreases human MSC‐derived osteoblast differentiation and mineralization in vitro
por: Both, Tim, et al.
Publicado: (2017)

Meeting report of the 2016 bone marrow adiposity meeting
por: van der Eerden, Bram, et al.
Publicado: (2017)

Fibronectin in Fracture Healing: Biological Mechanisms and Regenerative Avenues
por: Klavert, Jonathan, et al.
Publicado: (2021)

The RNA-Binding Protein ATXN2 is Expressed during Megakaryopoiesis and May Control Timing of Gene Expression
por: Hansen, Marten, et al.
Publicado: (2020)

Osteocalcin—A Versatile Bone-Derived Hormone
por: Moser, Sarah C., et al.
Publicado: (2019)

Truncated CSF3 receptors induce pro‐inflammatory responses in severe congenital neutropenia
por: Olofsen, Patricia A., et al.
Publicado: (2022)

S160: GATA2B HAPLOINSUFFICIENCY CAUSES ABERRANT TRANSCRIPTIONAL REGULATORY SIGNATURES IN HSPCS RESULTING IN MYELOID AND ERYTHROID DYSPLASIA IN ZEBRAFISH
por: Zhang, Wei, et al.
Publicado: (2023)

Identification of Chloride Intracellular Channel Protein 3 as a Novel Gene Affecting Human Bone Formation
por: Brum, Andrea M, et al.
Publicado: (2017)

MicroRNA-139, an Emerging Gate-Keeper in Various Types of Cancer
por: Stavast, Christiaan J., et al.
Publicado: (2022)

Induced cell-autonomous neutropenia systemically perturbs hematopoiesis in Cebpa enhancer-null mice
por: Avellino, Roberto, et al.
Publicado: (2022)

The presence of alpha-catenin in the VE-cadherin complex is required for efficient transendothelial migration of leukocytes
por: van Buul, Jaap D., et al.
Publicado: (2009)

Storage of Factor VIII Variants with Impaired von Willebrand Factor Binding in Weibel-Palade Bodies in Endothelial Cells
por: van den Biggelaar, Maartje, et al.
Publicado: (2011)

Serine phosphorylation of the RhoGEF Trio stabilizes endothelial cell-cell junctions
por: Daniel, Anna E., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_tq7vvtleq5kfa000bsiich9ede