Case Report: Epstein–Barr Virus Encephalitis Complicated With Brain Stem Hemorrhage in an Immune-Competent Adult

Encephalitis caused by Epstein-Barr virus infection is uncommon, but most patients have a good outcome after symptomatic treatment. The infiltration of mononuclear cells in blood vessels and necrosis resulting from the immune response to Epstein-Barr virus infection in a very small number of patient...

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Detalles Bibliográficos
Autores principales: Huang, Lingtong, Zhang, Xuan, Fang, Xueling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7947888/
https://www.ncbi.nlm.nih.gov/pubmed/33717113
http://dx.doi.org/10.3389/fimmu.2021.618830
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author Huang, Lingtong
Zhang, Xuan
Fang, Xueling
author_facet Huang, Lingtong
Zhang, Xuan
Fang, Xueling
author_sort Huang, Lingtong
collection PubMed
description Encephalitis caused by Epstein-Barr virus infection is uncommon, but most patients have a good outcome after symptomatic treatment. The infiltration of mononuclear cells in blood vessels and necrosis resulting from the immune response to Epstein-Barr virus infection in a very small number of patients seem to be the main cause of death. We describe a fatal case of Epstein-Barr virus encephalitis diagnosed by next-generation sequencing in an immune-competent adult but progressed to brainstem hemorrhage.
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spelling pubmed-79478882021-03-12 Case Report: Epstein–Barr Virus Encephalitis Complicated With Brain Stem Hemorrhage in an Immune-Competent Adult Huang, Lingtong Zhang, Xuan Fang, Xueling Front Immunol Immunology Encephalitis caused by Epstein-Barr virus infection is uncommon, but most patients have a good outcome after symptomatic treatment. The infiltration of mononuclear cells in blood vessels and necrosis resulting from the immune response to Epstein-Barr virus infection in a very small number of patients seem to be the main cause of death. We describe a fatal case of Epstein-Barr virus encephalitis diagnosed by next-generation sequencing in an immune-competent adult but progressed to brainstem hemorrhage. Frontiers Media S.A. 2021-02-25 /pmc/articles/PMC7947888/ /pubmed/33717113 http://dx.doi.org/10.3389/fimmu.2021.618830 Text en Copyright © 2021 Huang, Zhang and Fang http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Immunology
Huang, Lingtong
Zhang, Xuan
Fang, Xueling
Case Report: Epstein–Barr Virus Encephalitis Complicated With Brain Stem Hemorrhage in an Immune-Competent Adult
title Case Report: Epstein–Barr Virus Encephalitis Complicated With Brain Stem Hemorrhage in an Immune-Competent Adult
title_full Case Report: Epstein–Barr Virus Encephalitis Complicated With Brain Stem Hemorrhage in an Immune-Competent Adult
title_fullStr Case Report: Epstein–Barr Virus Encephalitis Complicated With Brain Stem Hemorrhage in an Immune-Competent Adult
title_full_unstemmed Case Report: Epstein–Barr Virus Encephalitis Complicated With Brain Stem Hemorrhage in an Immune-Competent Adult
title_short Case Report: Epstein–Barr Virus Encephalitis Complicated With Brain Stem Hemorrhage in an Immune-Competent Adult
title_sort case report: epstein–barr virus encephalitis complicated with brain stem hemorrhage in an immune-competent adult
topic Immunology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7947888/
https://www.ncbi.nlm.nih.gov/pubmed/33717113
http://dx.doi.org/10.3389/fimmu.2021.618830
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