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Histone deacetylase 4 inhibits NF-κB activation by facilitating IκBα sumoylation

Protein modification by small ubiquitin-like modifier (SUMO) is an important regulatory mechanism for multiple cellular processes. Although the canonical pathway involving the ubiquitylation or phosphorylation of IκBα has been well characterized, little is known about the sumoylation of IκBα in the...

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Detalles Bibliográficos
Autores principales: Yang, Qi, Tang, Jielin, Xu, Chonghui, Zhao, He, Zhou, Yuan, Wang, Yanyi, Yang, Min, Chen, Xinwen, Chen, Jizheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948076/
https://www.ncbi.nlm.nih.gov/pubmed/32770227
http://dx.doi.org/10.1093/jmcb/mjaa043