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ROS-dependent HIF1α activation under forced lipid catabolism entails glycolysis and mitophagy as mediators of higher proliferation rate in cervical cancer cells
BACKGROUND: In the last decades, the concept of metabolic rewiring as a cancer hallmark has been expanded beyond the “Warburg effect” and the importance of other metabolic routes, including lipid metabolism, has emerged. In cancer, lipids are not only a source of energy but are also required for the...
Autores principales: | Castelli, Serena, Ciccarone, Fabio, Tavian, Daniela, Ciriolo, Maria Rosa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948341/ https://www.ncbi.nlm.nih.gov/pubmed/33706793 http://dx.doi.org/10.1186/s13046-021-01887-w |
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