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Editing GWAS: experimental approaches to dissect and exploit disease-associated genetic variation

Genome-wide association studies (GWAS) have uncovered thousands of genetic variants that influence risk for human diseases and traits. Yet understanding the mechanisms by which these genetic variants, mainly noncoding, have an impact on associated diseases and traits remains a significant hurdle. In...

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Detalles Bibliográficos
Autores principales:	Rao, Shuquan, Yao, Yao, Bauer, Daniel E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948363/ https://www.ncbi.nlm.nih.gov/pubmed/33691767 http://dx.doi.org/10.1186/s13073-021-00857-3

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