Cargando…
Poor Head Growth Is Associated with Later Mental Delay among Vietnamese Preterm Infants: A Follow-up Study
BACKGROUND: Preterm infants in low- and middle-income countries are at high risk of poor physical growth, but their growth data are still scarce. OBJECTIVES: To describe the growth of Vietnamese preterm infants in the first 2 years, and to compare with references: World Health Organization (WHO) chi...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948389/ https://www.ncbi.nlm.nih.gov/pubmed/33346849 http://dx.doi.org/10.1093/tropej/fmaa117 |
_version_ | 1783663397381865472 |
---|---|
author | Do, Chuong Huu Thieu Børresen, Malene Landbo Pedersen, Freddy Karup Nguyen, Tinh Thu Nguyen, Hung Thanh Kruse, Alexandra Yasmin |
author_facet | Do, Chuong Huu Thieu Børresen, Malene Landbo Pedersen, Freddy Karup Nguyen, Tinh Thu Nguyen, Hung Thanh Kruse, Alexandra Yasmin |
author_sort | Do, Chuong Huu Thieu |
collection | PubMed |
description | BACKGROUND: Preterm infants in low- and middle-income countries are at high risk of poor physical growth, but their growth data are still scarce. OBJECTIVES: To describe the growth of Vietnamese preterm infants in the first 2 years, and to compare with references: World Health Organization (WHO) child growth standards, and healthy Southeast Asian (SEA) infants. Further, to assess the association between growth in the first year and neurodevelopment at 2 years corrected age (CA). METHODS: We conducted a cohort study to follow up preterm infants discharged from a neonatal intensive care unit for 2 years. Weight, length and head circumference (HC) were measured at 3, 12 and 24 months CA. Neurodevelopment was assessed using Bayley Scales of Infant and Toddler Development—3rd Edition at 24 months CA. RESULTS: Over 90% of the cohort showed catch-up weight at 3 months CA. Weight and length were comparable to healthy SEA but were lower than WHO standards. HC was significantly smaller than those of WHO standards with HC Z-scores steadily decreasing from −0.95 at 3 months CA to −1.50 at 24 months CA. Each one decrement of HC Z-score from 3 to 12 months CA was associated with nearly twice an increase in odds of mental delay at 24 months CA (odds ratio 1.89; 95% confidence interval 1.02–3.50). CONCLUSION: Vietnamese preterm infants exhibited early catch-up weight but poor head growth, which was associated with later delays in mental development. Our findings support the importance of HC measures in follow-up for preterm infants. |
format | Online Article Text |
id | pubmed-7948389 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-79483892021-03-16 Poor Head Growth Is Associated with Later Mental Delay among Vietnamese Preterm Infants: A Follow-up Study Do, Chuong Huu Thieu Børresen, Malene Landbo Pedersen, Freddy Karup Nguyen, Tinh Thu Nguyen, Hung Thanh Kruse, Alexandra Yasmin J Trop Pediatr Original Paper BACKGROUND: Preterm infants in low- and middle-income countries are at high risk of poor physical growth, but their growth data are still scarce. OBJECTIVES: To describe the growth of Vietnamese preterm infants in the first 2 years, and to compare with references: World Health Organization (WHO) child growth standards, and healthy Southeast Asian (SEA) infants. Further, to assess the association between growth in the first year and neurodevelopment at 2 years corrected age (CA). METHODS: We conducted a cohort study to follow up preterm infants discharged from a neonatal intensive care unit for 2 years. Weight, length and head circumference (HC) were measured at 3, 12 and 24 months CA. Neurodevelopment was assessed using Bayley Scales of Infant and Toddler Development—3rd Edition at 24 months CA. RESULTS: Over 90% of the cohort showed catch-up weight at 3 months CA. Weight and length were comparable to healthy SEA but were lower than WHO standards. HC was significantly smaller than those of WHO standards with HC Z-scores steadily decreasing from −0.95 at 3 months CA to −1.50 at 24 months CA. Each one decrement of HC Z-score from 3 to 12 months CA was associated with nearly twice an increase in odds of mental delay at 24 months CA (odds ratio 1.89; 95% confidence interval 1.02–3.50). CONCLUSION: Vietnamese preterm infants exhibited early catch-up weight but poor head growth, which was associated with later delays in mental development. Our findings support the importance of HC measures in follow-up for preterm infants. Oxford University Press 2020-12-21 /pmc/articles/PMC7948389/ /pubmed/33346849 http://dx.doi.org/10.1093/tropej/fmaa117 Text en © The Author(s) [2020]. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Original Paper Do, Chuong Huu Thieu Børresen, Malene Landbo Pedersen, Freddy Karup Nguyen, Tinh Thu Nguyen, Hung Thanh Kruse, Alexandra Yasmin Poor Head Growth Is Associated with Later Mental Delay among Vietnamese Preterm Infants: A Follow-up Study |
title | Poor Head Growth Is Associated with Later Mental Delay among Vietnamese Preterm Infants: A Follow-up Study |
title_full | Poor Head Growth Is Associated with Later Mental Delay among Vietnamese Preterm Infants: A Follow-up Study |
title_fullStr | Poor Head Growth Is Associated with Later Mental Delay among Vietnamese Preterm Infants: A Follow-up Study |
title_full_unstemmed | Poor Head Growth Is Associated with Later Mental Delay among Vietnamese Preterm Infants: A Follow-up Study |
title_short | Poor Head Growth Is Associated with Later Mental Delay among Vietnamese Preterm Infants: A Follow-up Study |
title_sort | poor head growth is associated with later mental delay among vietnamese preterm infants: a follow-up study |
topic | Original Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948389/ https://www.ncbi.nlm.nih.gov/pubmed/33346849 http://dx.doi.org/10.1093/tropej/fmaa117 |
work_keys_str_mv | AT dochuonghuuthieu poorheadgrowthisassociatedwithlatermentaldelayamongvietnamesepreterminfantsafollowupstudy AT børresenmalenelandbo poorheadgrowthisassociatedwithlatermentaldelayamongvietnamesepreterminfantsafollowupstudy AT pedersenfreddykarup poorheadgrowthisassociatedwithlatermentaldelayamongvietnamesepreterminfantsafollowupstudy AT nguyentinhthu poorheadgrowthisassociatedwithlatermentaldelayamongvietnamesepreterminfantsafollowupstudy AT nguyenhungthanh poorheadgrowthisassociatedwithlatermentaldelayamongvietnamesepreterminfantsafollowupstudy AT krusealexandrayasmin poorheadgrowthisassociatedwithlatermentaldelayamongvietnamesepreterminfantsafollowupstudy |