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Phosphorylation of the RB C-terminus regulates condensin II release from chromatin

The retinoblastoma tumor suppressor protein (RB) plays an important role in biological processes such as cell cycle control, DNA damage repair, epigenetic regulation, and genome stability. The canonical model of RB regulation is that cyclin-CDKs phosphorylate and render RB inactive in late G1/S, pro...

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Detalles Bibliográficos
Autores principales: Kim, Seung J., MacDonald, James I., Dick, Frederick A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948394/
https://www.ncbi.nlm.nih.gov/pubmed/33219128
http://dx.doi.org/10.1074/jbc.RA120.016511