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Small-molecule control of neurotransmitter sulfonation
Controlling unmodified serotonin levels in brain synapses is a primary objective when treating major depressive disorder—a disease that afflicts ∼20% of the world’s population. Roughly 60% of patients respond poorly to first-line treatments and thus new therapeutic strategies are sought. To this end...
Autores principales: | Cook, Ian, Cacace, Mary, Wang, Ting, Darrah, Kristie, Deiters, Alexander, Leyh, Thomas S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948405/ https://www.ncbi.nlm.nih.gov/pubmed/33485192 http://dx.doi.org/10.1074/jbc.RA120.015177 |
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