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Salivary complement inhibitors from mosquitoes: Structure and mechanism of action
Inhibition of the alternative pathway (AP) of complement by saliva from Anopheles mosquitoes facilitates feeding by blocking production of the anaphylatoxins C3a and C5a, which activate mast cells leading to plasma extravasation, pain, and itching. We have previously shown that albicin, a member of...
Autores principales: | Strayer, Ethan C., Lu, Stephen, Ribeiro, Jose, Andersen, John F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948415/ https://www.ncbi.nlm.nih.gov/pubmed/33199367 http://dx.doi.org/10.1074/jbc.RA120.015230 |
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