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Salivary complement inhibitors from mosquitoes: Structure and mechanism of action

Inhibition of the alternative pathway (AP) of complement by saliva from Anopheles mosquitoes facilitates feeding by blocking production of the anaphylatoxins C3a and C5a, which activate mast cells leading to plasma extravasation, pain, and itching. We have previously shown that albicin, a member of...

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Detalles Bibliográficos
Autores principales: Strayer, Ethan C., Lu, Stephen, Ribeiro, Jose, Andersen, John F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948415/
https://www.ncbi.nlm.nih.gov/pubmed/33199367
http://dx.doi.org/10.1074/jbc.RA120.015230

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