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IQGAP1 binds AMPK and is required for maximum AMPK activation
AMP-activated protein kinase (AMPK) is a fundamental component of a protein kinase cascade that is an energy sensor. AMPK maintains energy homeostasis in the cell by promoting catabolic and inhibiting anabolic pathways. Activation of AMPK requires phosphorylation by the liver kinase B1 or by the Ca(...
Autores principales: | Hedman, Andrew C., Li, Zhigang, Gorisse, Laëtitia, Parvathaneni, Swetha, Morgan, Chase J., Sacks, David B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948462/ https://www.ncbi.nlm.nih.gov/pubmed/33191271 http://dx.doi.org/10.1074/jbc.RA120.016193 |
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