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ApoC-III is a novel inducer of calcification in human aortic valves

Calcific aortic valve disease (CAVD) occurs when subpopulations of valve cells undergo specific differentiation pathways, promoting tissue fibrosis and calcification. Lipoprotein particles carry oxidized lipids that promote valvular disease, but low-density lipoprotein–lowering therapies have failed...

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Detalles Bibliográficos
Autores principales:	Schlotter, Florian, de Freitas, Renata C.C., Rogers, Maximillian A., Blaser, Mark C., Wu, Pin-Jou, Higashi, Hideyuki, Halu, Arda, Iqbal, Farwah, Andraski, Allison B., Rodia, Cayla N., Kuraoka, Shiori, Wen, Jennifer R., Creager, Michael, Pham, Tan, Hutcheson, Joshua D., Body, Simon C., Kohan, Alison B., Sacks, Frank M., Aikawa, Masanori, Singh, Sasha A., Aikawa, Elena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948477/ https://www.ncbi.nlm.nih.gov/pubmed/33334888 http://dx.doi.org/10.1074/jbc.RA120.015700

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