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Fc γ receptor IIIa/CD16a processing correlates with the expression of glycan-related genes in human natural killer cells

Many therapeutic monoclonal antibodies require binding to Fc γ receptors (FcγRs) for full effect and increasing the binding affinity increases efficacy. Preeminent among the five activating human FcγRs is FcγRIIIa/CD16a expressed by natural killer (NK) cells. CD16a is heavily processed, and recent r...

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Detalles Bibliográficos
Autores principales:	Patel, Kashyap R., Rodriguez Benavente, Maria C., Lorenz, W. Walter, Mace, Emily M., Barb, Adam W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948478/ https://www.ncbi.nlm.nih.gov/pubmed/33310702 http://dx.doi.org/10.1074/jbc.RA120.015516

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