Genome editing demonstrates that the −5 kb Nanog enhancer regulates Nanog expression by modulating RNAPII initiation and/or recruitment

Transcriptional enhancers have been defined by their ability to operate independent of distance and orientation in plasmid-based reporter assays of gene expression. At present, histone marks are used to identify and define enhancers but do not consider the endogenous role of an enhancer in the conte...

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Detalles Bibliográficos
Autores principales: Agrawal, Puja, Blinka, Steven, Pulakanti, Kirthi, Reimer, Michael H., Stelloh, Cary, Meyer, Alison E., Rao, Sridhar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948488/
https://www.ncbi.nlm.nih.gov/pubmed/33334884
http://dx.doi.org/10.1074/jbc.RA120.015152

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948488/
https://www.ncbi.nlm.nih.gov/pubmed/33334884
http://dx.doi.org/10.1074/jbc.RA120.015152

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