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Dealing with difficult clients via personalized chaperone inhibitors
The importance of molecular chaperones in cancer is well established, yet several chaperone inhibitors have failed in clinical trials due to toxicity. Recent efforts have focused on targeting chaperone function in cancer by either manipulating the “chaperone code” or inhibiting helper cochaperones,...
Autor principal: | Truman, Andrew W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948493/ https://www.ncbi.nlm.nih.gov/pubmed/33837724 http://dx.doi.org/10.1016/j.jbc.2020.100211 |
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