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Dealing with difficult clients via personalized chaperone inhibitors

The importance of molecular chaperones in cancer is well established, yet several chaperone inhibitors have failed in clinical trials due to toxicity. Recent efforts have focused on targeting chaperone function in cancer by either manipulating the “chaperone code” or inhibiting helper cochaperones,...

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Detalles Bibliográficos
Autor principal: Truman, Andrew W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948493/
https://www.ncbi.nlm.nih.gov/pubmed/33837724
http://dx.doi.org/10.1016/j.jbc.2020.100211

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