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Active site metals mediate an oligomeric equilibrium in Plasmodium M17 aminopeptidases

M17 leucyl aminopeptidases are metal-dependent exopeptidases that rely on oligomerization to diversify their functional roles. The M17 aminopeptidases from Plasmodium falciparum (PfA-M17) and Plasmodium vivax (Pv-M17) function as catalytically active hexamers to generate free amino acids from human...

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Detalles Bibliográficos
Autores principales:	Malcolm, Tess R., Belousoff, Matthew J., Venugopal, Hariprasad, Borg, Natalie A., Drinkwater, Nyssa, Atkinson, Sarah C., McGowan, Sheena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948507/ https://www.ncbi.nlm.nih.gov/pubmed/33303633 http://dx.doi.org/10.1074/jbc.RA120.016313

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