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Dicer represses the interferon response and the double-stranded RNA-activated protein kinase pathway in mouse embryonic stem cells

Recent studies have demonstrated that embryonic stem cells (ESCs) are deficient in expressing type I interferons (IFN), the cytokines that play key roles in antiviral responses. However, the underlying molecular mechanisms and biological implications of this finding are poorly understood. In this st...

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Detalles Bibliográficos
Autores principales:	Gurung, Chandan, Fendereski, Mona, Sapkota, Krishna, Guo, Jason, Huang, Faqing, Guo, Yan-Lin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948645/ https://www.ncbi.nlm.nih.gov/pubmed/33837743 http://dx.doi.org/10.1016/j.jbc.2021.100264

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