Structures and mechanism of human glycosyltransferase β1,3-N-acetylglucosaminyltransferase 2 (B3GNT2), an important player in immune homeostasis

β1,3-N-acetylglucosaminyltransferases (B3GNTs) are Golgi-resident glycosyltransferases involved in the biosynthesis of poly-N-acetyl-lactosamine chains. They catalyze the addition of the N-acetylglucosamine to the N-acetyl-lactosamine repeat as a key step of the chain elongation process. Poly-N-acet...

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Detalles Bibliográficos
Autores principales: Hao, Yue, Créquer-Grandhomme, Amandine, Javier, Noelle, Singh, Aman, Chen, Hao, Manzanillo, Paolo, Lo, Mei-Chu, Huang, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948737/
https://www.ncbi.nlm.nih.gov/pubmed/33158990
http://dx.doi.org/10.1074/jbc.RA120.015306

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