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Cell autonomous angiotensin II signaling controls the pleiotropic functions of oncogenic K-Ras

Oncogenic K-Ras (K-Ras(G12V)) promotes senescence in normal cells but fuels transformation of cancer cells after the senescence barrier is bypassed. The mechanisms regulating this pleiotropic function of K-Ras remain to be fully established and bear high pathological significance. We find that K-Ras...

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Detalles Bibliográficos
Autores principales:	Volonte, Daniela, Sedorovitz, Morgan, Cespedes, Victoria E., Beecher, Maria L., Galbiati, Ferruccio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948762/ https://www.ncbi.nlm.nih.gov/pubmed/33380422 http://dx.doi.org/10.1074/jbc.RA120.015188

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