Androgen receptor splicing variant 7 (ARV7) inhibits docetaxel sensitivity by inactivating the spindle assembly checkpoint

The clinical efficacy of docetaxel (DTX) in prostate cancer treatment is barely satisfactory due to diverse responses of the patients, including the development of resistance. Recently, aberrant androgen receptor (AR) signaling, including expression of the constitutively active ARV7, was reported to...

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Detalles Bibliográficos
Autores principales: Yu, Bingbing, Liu, Yanan, Luo, Haoge, Fu, Jiaying, Li, Yang, Shao, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948795/
https://www.ncbi.nlm.nih.gov/pubmed/33428943
http://dx.doi.org/10.1016/j.jbc.2021.100276

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